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Sodium Mercaptoethane Sulfonate (Mesna) 100 mg/ml

Sodium Mercaptoethane Sulfonate (Mesna) 100 mg/ml

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Sodium Mercaptoethane Sulphate (Mensa) 100 mg/ml


Indications :

In reducing the incidence of ifosfamide - induced hemorrhagic cystitis.


Dosage :Adults bolus IV :

20% IV x 3 doses (0, 4 and 8 hours)

40% IV (0, 1, 4 and 7 hours)


Continuous IV :

20% IV pre-chemo, 50-100% with chemo, then 25-50% x 12 hours


Children :

60-160 % of Oxazaphosphorine dose.


Dosage Adjustment :

Renal Impairment : Administer with caution.

Hepatic Impairment : Administer with caution.