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Mitomycin for Injection USP 2 mg (Lyophilized)

Mitomycin for Injection USP 2 mg (Lyophilized)

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Mitomycin for Injection USP 2 mg (Lyophilized)

Indications :   

  • Gastro-intestinal Cancer (esophageal carcinoma)
  • Breast cancer
  • Superficial bladder tumours
  • Adenocarcinoma of stomach or pancreas
  • Non-small cell lung cancer
  • Head and neck squamous cell cancer
  • Colorectal cancer

Dosage :
AS SINGLE THERAPY : 12 - 14 mg/m² once a month or every 35 days by intravenous infusion.
The crystals are dissolved in 200 mL of a 5% glucose solution which is then administered over a period of 30 minutes, preferably with Vitamin B Compound.

AS COMBINATION THERAPY : 10 mg/m² every 6 - 9 weeks. Higher doses have also been given.
Mitomycin-C is usually administered along with other agents (e.g. FOAM –5 FU plus vincristine plus doxorubicin plus mitomycin; SMF –streptozotocin plus mitomycin plus 5 FU; AM – doxorubicin plus mitomycin; FAM –5 FU plus doxorubicin plus mitomycin).

Dosage Adjustment :

Renal Impairment : Required.

Hepatic Impairment : Not necessary but administer with caution.
       
Packing: 10 Vials of 2 mg

 

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Lyomit 10mg Injection Mitomycin-C 10mg
Lyomit 2mg Injection Mitomycin-C 2 mg